In the beginning God created an ordered, harmonious universe. It was a creation where everything had its place and function. It was a beautiful, good, and blessed creation. God also made special creatures: humans. Humans represented God in his creation. In addition, God created humans as relational beings. Humans were meant to relate to God (he walked alongside them,) to creation (they were the caretakers of the garden), and to each other (God instituted marriage and family life).
This verse is part of Jesus’ prayer of agony in the Garden of Gethsemane before His arrest and crucifixion. This “cup” to which He referred was the suffering He would endure on the cross as an atoning sacrifice for sin.